Styrene monomer does not induce unscheduled DNA synthesis in the mouse liver following inhalation exposure
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Styrene monomer does not induce unscheduled DNA synthesis in the mouse liver following inhalation exposure.
Styrene monomer is a commercially important chemical used extensively in the production of plastics. It has been shown to induce lung tumours in the mouse via the inhalation route. Styrene monomer has shown a low reactivity with DNA and also a lack of genotoxic response in the mouse lung in vivo. Together with the fact that the mouse lung tumours were late occurring and mostly benign, which sug...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2004
ISSN: 1464-3804
DOI: 10.1093/mutage/geh062